Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates
B. Bobály, G. M. Randazzo, S. Rudaz, D. Guillarme, Sz. Fekete
J. Chromatogr. A, 1481, 20 January, 82-91 (2017)
Keywords: Hydrophobic interaction chromatography, Antibody-drug-conjugate, Method development, Retention modeling, Non-linear gradient, DryLab, Method modeling
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http://doi.org/10.1016/j.chroma.2016.12.047