So far, more than 260 peer reviewed papers have been published on the application of DryLab – a complete list of which you can find here.
DryLab draws on the philosophy described in the three most famous Solvophobic Theory papers I, II, III of Csaba Horváth, which were developed in the years 1975-1977 at Yale University (see also literature by Dr. Imre Molnár).
First description of DryLab 4-5 (the ancestor of the binary isocratic reversed phase module of DryLab for Windows) as applied to a mixture of nitro-aromatic compounds.
Separation of peptide mixtures by reversed-phase gradient elution. Use of flow rate changes for controlling band spacing and improving resolution
J.L. Glajch, M.A. Quarry, J F. Vasta, L.R. Snyder Anal Chem., 58, 2, 280–285 (1986), DOI: 10.1021/ac00293a004
A general model has recently been proposed for the separation of peptides and proteins using reverse-phase gradient elution liquid chromatography. One application of this model suggests that flow rate, gradient time, or column configuration can be varied for band spacing control in the separation of enzymatic digests of proteins. Here a systematic procedure is described that uses repeated separations with different flow rates to maximize the separation of individual peaks within the chromatogram. From these initial separations it is possible to choose an optimum flow rate for the separation of a given sample. It is important in this approach to identify which bands in the various separations correspond to the same peptide. Various peak-tracking procedures are discussed and illustrated.
HPLC Separation of Large Molecules. A General Model.
L.R. Snyder, M.A. Stadalius High-Performance Liquid Chromatography. Advances and Perspectives (Vol. 4), in: Csaba Horváth (ed.), Academic Press, New York, 195, (1986)
Summary of the basic model that underlies DryLab G applied to large molecules.
Selecting Column Conditions for Reversed-Phase HPLC Separation II. Column Configuration and Column Evaluation
L.R. Snyder, P.E. Antle LC·GC, 3, 98 (1985)
Optimization model for the gradient elution separation of peptide mixtures by reversed-phase high-performance liquid chromatography : Application to method development and the choice of column configuration
M.A. Stadalius, M.A. Quarry
L.R. SnyderM.A. Stadalius, M.A. Quarry
L.R. Snyder J. Chromatogr. A, 327, 93–113 (1985), DOI: 10.1016/S0021-9673(01)81640-X