Lecture at ISPE 2016 in Frankfurt, Germany
On Tuesday, October 25th, Imre Molnár lectured at the International Society for Pharmaceutical Engineering's Annual Meeting in Frankfurt on regulatory highlights, namely on 'Reduce Time to Market by Data Modelling in Analytics of Biopharmaceuticals'
Analysis of mAb's and ADC's
The team of Szabolcs Fekete and Davy Guillarme (Univ. Geneva, CH) contributed two new papers about the analysis of monoclonal antibodies (mAb’s) and conjugated molecules in Journal of Pharmaceutical and Biomedical Analysis. The technique applied was Hydrophobic Interaction Chromatography (HIC), which seems to work with antibody-drug-conjugates (ADC’s) with great success, opening up new capabilities in the field of effective cancer treatment. The best separation conditions were found fast with the newest DryLab4-HPLC-method development software, developed by Molnár-Institute, Berlin. Analysis time was typically less than 10 min, method development time is approximately half a day.
Read more in our literature section!